Use of ethyl glucuronide and ethyl sulphate in forensic toxicology
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منابع مشابه
Biochemical Markers of Acute and Chronic Ethanol Use: Forensic and Clinical Applications
Background: The analysis of ethanol in bio-samples is an important method for determination of acute alcohol use/abuse both in clinical and forensic toxicology. In forensic cases, it is known that micro-organisms involved in the postmortem putrefaction process can produce alcohol and when the body has been traumatized. In clinical setting, post-ingestion time has a critical role for determinati...
متن کاملSerum/whole blood concentration ratio for ethylglucuronide and ethyl sulfate.
Serum/blood (S/B) concentration ratios for ethyl glucuronide (EtG) and ethyl sulfate (EtS) are missing from the literature, and the aim of this study was to determine these ratios in samples from patients at admission to an alcohol rehabilitation clinic. Two blood samples were collected simultaneously, and EtG and EtS were analyzed in whole blood and serum, respectively, using a liquid chromato...
متن کاملEthyl Glucuronide Determination in Hair as an Indicator of Chronic Alcohol Abuse: a Fully Validated Method by Gc-ei-ms/ms
Hair analysis is a powerful tool for the detection of chronic or past drug ingestion and in recent years it has also been exploited for chronic alcohol abuse. Ethyl glucuronide (EtG) determination in hair has been increasingly employed for diagnosing chronic excessive drinking in both clinical and forensic areas. This work describes a simple fully validated method for the determination of EtG i...
متن کاملUtility of urinary ethyl glucuronide analysis in post-mortem toxicology when investigating alcohol-related deaths.
Use and abuse of alcohol are common findings when unnatural deaths are investigated as evidenced by high blood- and urine- alcohol concentrations (BAC and UAC) at autopsy. Because ethanol is metabolized in the liver until the time of death, the autopsy BAC or UAC might be negative even though the deceased had consumed alcohol in the immediate ante-mortem period. Analysis of the non-oxidative me...
متن کاملForensic toxicology.
Forensic toxicology is a discipline of analytical toxicology dedicated to toxicological problems of forensic relevance, for example driving under the influence of alcohol or drugs, or postmortem toxicology. High-quality analytical methods for identification and quantification of drugs, poisons, and/or their metabolites in complex matrices, for example body fluids or hair, are very important in ...
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